A polymer gel index-matched to water enables diverse applications in fluorescence imaging
(Hari Shroff et al, October 2020)
This publication shows how BIO-133 can be used to enable multiple applications in fluorescence imaging.
The research covers the following issues:
(1) Characterization of BIO-133 for optical imaging in microfluidic/immobilization setups;
(2) Showing that diffraction-limited and super-resolution imaging is possible when using this material;
(3) Showing that high-resolution light-sheet microscopy with water-dipping objectives is fully compatible with microfluidic setups, a goal thought by many in the field to be impossible;